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<h1 style="color: #000 !important;">Abstract 20151020</h1>
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<p><strong style="background-color: initial;"><의공학연구소 정례세미나></strong></p><p><strong>연자 : 이현나 교수 (서울대학교 뇌인지과학사업단)</strong></p><p><strong>주제 : Neuroimaging for early diagnosis of AD</strong></p><p><strong>일시 : 10월 20일 화요일 17:00~</strong></p><p><strong>장소 : 아산생명과학연구원 교육연구관 4층 회의실</strong></p><p><strong><br></strong></p><p><strong><abstract></abstract></strong></p><p><strong><br></strong></p><p>Alzheimer’s disease (AD) is the most common
cause of dementia in the elderly. It is now well-established that by the time
dementia manifests clinically in an individual, the disease has been present
for many years, possibly decades. With the rapid advances in technology, it is
now possible to detect abnormalities in the brains of patients much before the
development of dementia. This is particularly significant for the development
of disease modifying treatments. In this seminar, we will discuss the latest magnetic
resonance imaging (MRI) and positron emission tomography (PET) techniques for
the diagnosis of preclinical and early clinical AD. MRI includes the structural
imaging measures of brain atrophy, volumes of specific structures such as the
hippocampus and entorhinal cortex, cortical thickness and surface morphology.
Functional MRI includes diffusion tensor imaging (DTI), blood oxygen level
dependent (BOLD) imaging and perfusion imaging using other techniques. For PET,
the older technique for glucose metabolic rate using deoxyglucose is now
supplemented with amyloid and tau imaging. These techniques are beginning to
transform early diagnosis in AD, and it is likely that many of these will
become common place in the assessment of dementia patients in the future.</p>
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